Basic Information
ID: ALA4134307
Type: Functional
Description: Antagonist activity at recombinant human CCR4 expressed in CHO-K1 cells assessed as inhibition of CCL22 induced Ca2+ mobilization after 2 hrs by FMAT based fluorescence assay
Organism: Homo sapiens
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA4134307
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 384.66 | 2.76 | 2.76 |
| 413.08 | 3.36 | 3.36 |
| 463.56 | 3.53 | 3.53 |
| 392.65 | 3.25 | 3.25 |
| 378.24 | 2.39 | 2.39 |
| 398.66 | 2.74 | 2.74 |
| 402.18 | 3.61 | 3.61 |
| 419.11 | 3.42 | 3.42 |
| 412.28 | 2.00 | 2.00 |
| 446.70 | 3.61 | 3.61 |
| 370.16 | 2.87 | 2.87 |
| 413.08 | 3.36 | 3.36 |
| 352.17 | 2.73 | 2.73 |
| 413.08 | 3.36 | 3.36 |
| 348.21 | 2.90 | 2.90 |
| 340.21 | 2.65 | 2.65 |
| 368.63 | 3.25 | 3.25 |
| 398.69 | 3.15 | 3.15 |
| 382.69 | 3.32 | 3.32 |
| 368.63 | 3.25 | 3.25 |
| 378.63 | 2.70 | 2.70 |
| 383.68 | 2.80 | 2.80 |
| 413.08 | 3.36 | 3.36 |
| 378.63 | 2.70 | 2.70 |
| 445.71 | 4.21 | 4.21 |
| 348.21 | 2.90 | 2.90 |
| 364.21 | 2.09 | 2.09 |
| 369.62 | 2.64 | 2.64 |
| 334.18 | 2.59 | 2.59 |
| 424.74 | 4.66 | 4.66 |
| 413.08 | 3.36 | 3.36 |
| 426.32 | 3.78 | 3.78 |
| 410.71 | 4.27 | 4.27 |
| 359.19 | 2.46 | 2.46 |
| 350.22 | 2.11 | 2.11 |
| 348.21 | 2.90 | 2.90 |
| 352.17 | 2.73 | 2.73 |
| 474.75 | 4.31 | 4.31 |
| 352.17 | 2.73 | 2.73 |
| 279.75 | 1.68 | 1.68 |
| 374.66 | 3.31 | 3.31 |
| 413.08 | 3.36 | 3.36 |
| 350.22 | 2.11 | 2.11 |
| 400.73 | 3.48 | 3.48 |
| 344.19 | 2.05 | 2.05 |
| 523.62 | 5.58 | 5.58 |
| 378.24 | 2.99 | 2.99 |
| 352.17 | 2.73 | 2.73 |
| 455.16 | 4.53 | 4.53 |
| 378.63 | 2.70 | 2.70 |