Basic Information
ID: ALA4134393
Type: Binding
Description: Inhibition of DHCR24-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate incorporation into newly synthesized cholesterol after 24 hrs GC/MS analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4134393
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 401.64 | 5.43 | 5.43 |
| 438.01 | 5.85 | 5.85 |
| 480.43 | 4.95 | 4.95 |
| 424.07 | 5.25 | 5.25 |
| 415.62 | 5.22 | 5.22 |
| 431.62 | 5.20 | 5.20 |
| 459.67 | 5.24 | 5.24 |
| 443.67 | 6.00 | 6.00 |
| 377.34 | 3.20 | 3.20 |
| 403.56 | 4.64 | 4.64 |
| 401.59 | 4.88 | 4.88 |
| 387.61 | 5.35 | 5.35 |
| 374.57 | 5.13 | 5.13 |
| 332.53 | 4.55 | 4.55 |
| 442.64 | 6.25 | 6.25 |
| 388.55 | 5.22 | 5.22 |
| 373.58 | 5.09 | 5.09 |
| 402.58 | 5.31 | 5.31 |
| 457.70 | 6.25 | 6.25 |
| 547.57 | 6.10 | 6.10 |
| 429.65 | 5.66 | 5.66 |
| 443.67 | 6.05 | 6.05 |
| 456.67 | 6.64 | 6.64 |
| 417.59 | 4.81 | 4.81 |
| 372.55 | 5.33 | 5.33 |
| 318.50 | 4.31 | 4.31 |
| 457.70 | 6.39 | 6.39 |
| 332.53 | 4.55 | 4.55 |