Basic Information
ID: ALA4135161
Type: Binding
Description: Inhibition of human recombinant N-terminal His/GST-tagged LSD1 (172 to 852 residues) expressed in baculovirus infected insect cells using biotin-labeled H3K4me2 (1 to 24 residues) as substrate after 1 hr by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4135161
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 133.19 | 1.50 | 1.50 |
| 230.35 | 2.40 | 2.40 |
| 278.83 | 1.91 | 1.91 |
| 181.67 | 1.28 | 1.28 |
| 278.83 | 2.18 | 2.18 |
| 181.67 | 1.28 | 1.28 |
| 290.77 | 2.65 | 2.65 |
| 181.67 | 1.28 | 1.28 |
| 278.83 | 2.18 | 2.18 |
| 257.76 | 2.95 | 2.95 |
| 275.75 | 3.09 | 3.09 |
| 257.76 | 2.95 | 2.95 |
| 260.56 | 2.05 | 2.05 |
| 278.83 | 2.18 | 2.18 |
| 278.83 | 1.91 | 1.91 |
| 275.75 | 3.09 | 3.09 |
| 302.81 | 2.52 | 2.52 |
| 302.81 | 2.52 | 2.52 |
| 260.56 | 2.05 | 2.05 |
| 290.77 | 2.65 | 2.65 |
| 181.67 | 1.28 | 1.28 |
| 278.83 | 2.18 | 2.18 |