Assay Report Card

Basic Information

ID: ALA4135234

Type: Binding

Description: Inhibition of Trypanosoma brucei pteridine reductase 1 assessed as reduction in conversion of dihydrobiopterin to tetrahydrobiopterin at 10 uM up to 50 mins in presence of NADPH by cytochrome c reduction coupled photometric assay relative to control

Organism: Trypanosoma brucei

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
332.273.023.02
366.334.474.47
374.303.243.24
346.293.323.32
346.293.323.32
374.303.243.24