Basic Information
ID: ALA4135242
Type: Binding
Description: Inhibition of RNH activity of recombinant HIV1 reverse transcriptase RNase H assessed as reduction in internal cleavage of RNA strand using RNA/DNA duplex substrate HTS-1
Organism: Human immunodeficiency virus 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4135242
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 184.18 | -0.01 | -0.01 |
| 198.20 | 0.30 | 0.30 |
| 260.27 | 1.66 | 1.66 |
| 444.42 | 0.91 | 0.91 |
| 254.25 | 1.59 | 1.59 |
| 305.79 | 0.06 | 0.06 |
| 260.27 | 1.66 | 1.66 |
| 294.72 | 2.31 | 2.31 |
| 294.72 | 2.31 | 2.31 |
| 367.86 | 1.24 | 1.24 |
| 226.26 | 0.52 | 0.52 |
| 288.69 | 2.25 | 2.25 |
| 240.28 | 0.91 | 0.91 |
| 278.26 | 1.79 | 1.79 |
| 253.26 | 2.27 | 2.27 |
| 311.77 | 0.82 | 0.82 |
| 274.30 | 1.58 | 1.58 |
| 242.21 | 0.00 | 0.00 |
| 212.23 | 0.61 | 0.61 |
| 322.18 | -0.67 | -0.67 |
| 260.27 | 1.66 | 1.66 |