Basic Information
ID: ALA4135331
Type: Binding
Description: Inhibition of TSPO in mouse HT22 cells assessed as recovery of ATP production at 5 uM preincubated for 10 mins followed by amyloid beta (1 to 42) stimulation and measured after 7 hrs by luciferase based assay relative to control
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4135331
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 319.19 | 3.81 | 3.81 |
| 1202.63 | ||
| 329.20 | 3.26 | 3.26 |
| 382.51 | 4.26 | 4.26 |
| 410.85 | 4.85 | 4.85 |
| 276.36 | 2.18 | 2.18 |
| 264.33 | 2.81 | 2.81 |
| 426.54 | 3.77 | 3.77 |
| 442.57 | 4.56 | 4.56 |
| 396.54 | 4.39 | 4.39 |
| 462.98 | 4.91 | 4.91 |
| 451.62 | 4.26 | 4.26 |
| 414.51 | 4.00 | 4.00 |
| 368.46 | 3.23 | 3.23 |
| 306.39 | 2.25 | 2.25 |
| 327.86 | 3.93 | 3.93 |
| 410.54 | 4.07 | 4.07 |
| 416.96 | 4.91 | 4.91 |
| 382.51 | 4.32 | 4.32 |
| 410.57 | 4.65 | 4.65 |
| 421.53 | 2.62 | 2.62 |
| 437.59 | 3.95 | 3.95 |
| 363.41 | 3.62 | 3.62 |
| 365.82 | 4.71 | 4.71 |
| 378.46 | 3.64 | 3.64 |
| 394.50 | 3.38 | 3.38 |
| 366.45 | 2.99 | 2.99 |
| 359.41 | 2.95 | 2.95 |
| 304.38 | 1.42 | 1.42 |
| 382.51 | 3.97 | 3.97 |
| 428.54 | 4.25 | 4.25 |
| 382.51 | 4.55 | 4.55 |
| 424.60 | 4.96 | 4.96 |
| 437.59 | 4.00 | 4.00 |
| 304.38 | 1.36 | 1.36 |
| 305.33 | 4.04 | 4.04 |
| 354.46 | 3.98 | 3.98 |
| 310.42 | 3.73 | 3.73 |
| 348.45 | 3.02 | 3.02 |
| 412.47 | 2.93 | 2.93 |
| 392.57 | 5.29 | 5.29 |
| 368.49 | 3.66 | 3.66 |
| 472.04 | 4.60 | 4.60 |
| 328.46 | 3.67 | 3.67 |
| 368.49 | 4.01 | 4.01 |
| 394.50 | 3.32 | 3.32 |
| 308.31 | 1.67 | 1.67 |
| 402.93 | 4.89 | 4.89 |
| 324.45 | 3.99 | 3.99 |
| 412.47 | 2.98 | 2.98 |
| 423.57 | 3.69 | 3.69 |
| 382.51 | 3.91 | 3.91 |
| 396.54 | 4.57 | 4.57 |
| 310.81 | 3.41 | 3.41 |
| 397.29 | 2.70 | 2.70 |
| 366.45 | 2.94 | 2.94 |
| 396.54 | 4.22 | 4.22 |
| 410.57 | 4.70 | 4.70 |
| 325.36 | 2.83 | 2.83 |
| 342.42 | 3.36 | 3.36 |
| 368.49 | 4.29 | 4.29 |
| 368.49 | 4.24 | 4.24 |
| 361.46 | 3.49 | 3.49 |