Basic Information
ID: ALA4135892
Type: ADME
Description: Metabolic stability in rat liver microsomes assessed as parent compound remaining at 10 uM preincubated for 10 mins followed by NADPH addition measured after 30 mins by liquid chromatographic method
Organism: Rattus norvegicus
Tissue: Liver
Subcellular Fraction: microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA4135892
Stability
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 555.68 | 5.33 | 5.33 |
| 520.99 | 4.94 | 4.94 |
| 497.56 | 4.66 | 4.66 |
| 552.55 | 5.05 | 5.05 |
| 488.54 | 4.73 | 4.73 |
| 482.58 | 4.76 | 4.76 |
| 483.53 | 4.05 | 4.05 |
| 540.52 | 5.18 | 5.18 |
| 508.96 | 5.07 | 5.07 |
| 459.51 | 3.57 | 3.57 |
| 452.56 | 4.75 | 4.75 |
| 500.57 | 4.60 | 4.60 |
| 470.55 | 4.89 | 4.89 |
| 482.58 | 4.76 | 4.76 |
| 552.55 | 5.05 | 5.05 |
| 488.54 | 4.73 | 4.73 |
| 520.99 | 4.94 | 4.94 |
| 540.52 | 5.18 | 5.18 |
| 459.51 | 3.57 | 3.57 |
| 483.53 | 4.05 | 4.05 |
| 497.56 | 4.66 | 4.66 |
| 508.96 | 5.07 | 5.07 |
| 470.55 | 4.89 | 4.89 |
| 452.56 | 4.75 | 4.75 |
| 500.57 | 4.60 | 4.60 |