Basic Information
ID: ALA4136449
Type: Binding
Description: Inhibition of recombinant human N-terminal GST-tagged ROS1 cytoplasmic domain (1883 to 2347 residues) expressed in baculovirus expression system using peptide substrate after 1 hr by mobility shift assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Proto-oncogene tyrosine-protein kinase ROS(ALA5568)
Document: ALA4130574
Inhibition of recombinant human N-terminal GST-tagged ROS1 cytoplasmic domain (1883 to 2347 residues) expressed in baculovirus expression system using peptide substrate after 1 hr by mobility shift assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4136449
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 450.35 | 5.04 | 5.04 |
| 558.15 | 6.36 | 6.36 |
| 627.24 | 7.16 | 7.16 |
| 686.30 | 5.82 | 5.82 |
| 656.28 | 6.46 | 6.46 |
| 598.13 | 3.79 | 3.79 |
| 626.19 | 4.57 | 4.57 |
| 628.22 | 5.68 | 5.68 |
| 611.17 | 5.62 | 5.62 |
| 612.16 | 4.14 | 4.14 |