Basic Information
ID: ALA4136961
Type: Binding
Description: Inhibition of recombinant human GST-tagged EPAC1 (149 to 881 residues) expressed in Escherichia coli Rosetta 2(DE3) assessed as reduction in guanine nucleotide exchange activity at 10 uM using BODIPY-labeled GDP loaded Rap1A by fluorescence assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4136961
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 272.12 | 2.89 | 2.89 |
| 351.01 | 3.65 | 3.65 |
| 193.22 | 2.12 | 2.12 |
| 323.00 | 4.10 | 4.10 |
| 365.04 | 4.04 | 4.04 |
| 193.22 | 2.12 | 2.12 |
| 323.00 | 4.10 | 4.10 |
| 272.12 | 2.89 | 2.89 |
| 323.00 | 4.10 | 4.10 |
| 272.12 | 2.89 | 2.89 |
| 193.22 | 2.12 | 2.12 |
| 429.91 | 4.41 | 4.41 |