ID: ALA4137467
Type: Binding
Description: Inhibition of human DNMT1 using polydeoxyinosine polydeoxycytosine DNA as substrate after 15 mins in presence of SAM by TR-FRET assay
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA4137467
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
244.21 | -3.17 | -3.17 |
490.65 | 3.87 | 3.87 |
228.21 | -2.14 | -2.14 |
509.74 | 5.84 | 5.84 |
461.53 | 5.65 | 5.65 |
546.71 | 5.02 | 5.02 |
494.71 | 5.65 | 5.65 |
480.70 | 5.66 | 5.66 |
521.71 | 4.98 | 4.98 |
492.66 | 5.44 | 5.44 |
478.64 | 4.01 | 4.01 |
508.75 | 6.44 | 6.44 |
504.68 | 5.72 | 5.72 |
491.64 | 3.97 | 3.97 |
496.70 | 3.37 | 3.37 |
464.61 | 4.84 | 4.84 |
412.58 | 3.92 | 3.92 |
489.62 | 4.75 | 4.75 |
475.64 | 4.68 | 4.68 |
482.67 | 4.85 | 4.85 |
540.71 | 6.54 | 6.54 |
466.55 | 4.63 | 4.63 |
521.71 | 4.94 | 4.94 |
482.67 | 4.51 | 4.51 |
478.64 | 4.01 | 4.01 |
478.64 | 5.18 | 5.18 |
477.65 | 4.92 | 4.92 |
479.63 | 4.58 | 4.58 |
506.69 | 5.96 | 5.96 |
428.58 | 3.62 | 3.62 |
520.72 | 6.22 | 6.22 |
464.61 | 4.87 | 4.87 |
478.68 | 5.57 | 5.57 |
514.67 | 6.03 | 6.03 |
474.65 | 5.28 | 5.28 |
494.64 | 4.37 | 4.37 |
488.68 | 5.59 | 5.59 |
518.70 | 5.97 | 5.97 |
480.65 | 4.42 | 4.42 |