Basic Information
ID: ALA4138596
Type: Binding
Description: Inhibition of calf thymus topoisomerase 1 assessed as suppression of relaxation of supercoiled pBR322 DNA at 100 uM incubated for 0.5 hrs by bromophenol blue and xylene cyanol FF staining based electrophoresis method
Format: BAO_0000357
Organism: Bos taurus
Target: Topoisomerase I(ALA6023)
Document: ALA4138059
Inhibition of calf thymus topoisomerase 1 assessed as suppression of relaxation of supercoiled pBR322 DNA at 100 uM incubated for 0.5 hrs by bromophenol blue and xylene cyanol FF staining based electrophoresis method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4138596
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 348.36 | 2.08 | 2.08 |
| 217.27 | 1.41 | 1.41 |
| 662.87 | 4.27 | 4.27 |
| 710.92 | 4.49 | 4.49 |
| 688.91 | 4.51 | 4.51 |
| 688.91 | 4.51 | 4.51 |
| 682.86 | 4.63 | 4.63 |
| 380.49 | 3.16 | 3.16 |
| 710.92 | 4.49 | 4.49 |
| 682.86 | 4.63 | 4.63 |
| 688.91 | 4.51 | 4.51 |
| 648.84 | 3.88 | 3.88 |
| 682.86 | 4.63 | 4.63 |
| 710.92 | 4.49 | 4.49 |