Potency index, ratio of enzyme inhibition of securinine to enzyme inhibition of test compound for inhibition of calf thymus topoisomerase 1 assessed a...

Basic Information

ID: ALA4138597

Type: Binding

Description: Potency index, ratio of enzyme inhibition of securinine to enzyme inhibition of test compound for inhibition of calf thymus topoisomerase 1 assessed as suppression of relaxation of supercoiled pBR322 DNA at 100 uM incubated for 0.5 hrs by bromophenol blue and xylene cyanol FF staining based electrophoresis method

Format: BAO_0000357

Organism: Bos taurus

Target:  Topoisomerase I(ALA6023)

Document:  ALA4138059

Potency index, ratio of enzyme inhibition of securinine to enzyme inhibition of test compound for inhibition of calf thymus topoisomerase 1 assessed as suppression of relaxation of supercoiled pBR322 DNA at 100 uM incubated for 0.5 hrs by bromophenol blue and xylene cyanol FF staining based electrophoresis method: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
682.864.634.63