Basic Information
ID: ALA4138598
Type: Binding
Description: Inhibition of calf thymus topoisomerase 1 assessed as reduction in topo1/DNA complex formation at 50 to 400 uM pre-incubated for 0.33 hrs before addition of supercoiled pBR322 DNA substrate by EMSA
Format: BAO_0000357
Organism: Bos taurus
Target: Topoisomerase I(ALA6023)
Document: ALA4138059
Inhibition of calf thymus topoisomerase 1 assessed as reduction in topo1/DNA complex formation at 50 to 400 uM pre-incubated for 0.33 hrs before addition of supercoiled pBR322 DNA substrate by EMSA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4138598
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 682.86 | 4.63 | 4.63 |