Basic Information
ID: ALA4138599
Type: Binding
Description: Inhibition of calf thymus topoisomerase 1 assessed as increase in nicked DNA at 50 uM using supercoiled pBR322 DNA incubated for 0.5 hrs by ethidium bromide staining based DNA-cleavage assay
Format: BAO_0000357
Organism: Bos taurus
Target: Topoisomerase I(ALA6023)
Document: ALA4138059
Inhibition of calf thymus topoisomerase 1 assessed as increase in nicked DNA at 50 uM using supercoiled pBR322 DNA incubated for 0.5 hrs by ethidium bromide staining based DNA-cleavage assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4138599
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 348.36 | 2.08 | 2.08 |
| 662.87 | 4.27 | 4.27 |
| 380.49 | 3.16 | 3.16 |
| 688.91 | 4.51 | 4.51 |