Assay Report Card

Basic Information

ID: ALA4138600

Type: Binding

Description: Inhibition of calf thymus topoisomerase 1 assessed as increase in nicked DNA at 10 uM using supercoiled pBR322 DNA incubated for 0.5 hrs by ethidium bromide staining based DNA-cleavage assay

Organism: Bos taurus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
348.362.082.08
662.874.274.27
380.493.163.16
688.914.514.51
682.864.634.63