Basic Information
ID: ALA4138601
Type: Binding
Description: Induction of DNA intercalation assessed as reduction in topoisomerase 1-mediated DNA relaxation at 100 uM using supercoiled pBR322 DNA incubated for 0.5 hrs in presence of calf thymus topoisomerase 1 by electrophoresis method
Format: BAO_0000019
Organism: Escherichia coli
Target: Unchecked(ALA612545)
Document: ALA4138059
Induction of DNA intercalation assessed as reduction in topoisomerase 1-mediated DNA relaxation at 100 uM using supercoiled pBR322 DNA incubated for 0.5 hrs in presence of calf thymus topoisomerase 1 by electrophoresis method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4138601
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 394.32 | 4.13 | 4.13 |
| 710.92 | 4.49 | 4.49 |
| 682.86 | 4.63 | 4.63 |
| 710.92 | 4.49 | 4.49 |
| 682.86 | 4.63 | 4.63 |
| 682.86 | 4.63 | 4.63 |
| 710.92 | 4.49 | 4.49 |