Basic Information
ID: ALA4138640
Type: Binding
Description: Inhibition of PRMT5 (unknown origin) assessed as reduction in methyl transfer from [3H]-SAM to biotinylated histone H4 peptide H4-20-Biotin at 100 uM pre-incubated for 3 mins before [3H]-SAM addition and measured after 45 mins by scintillation proximity assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4138640
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 340.43 | 2.88 | 2.88 |
| 324.38 | 2.27 | 2.27 |
| 312.37 | 2.10 | 2.10 |
| 354.45 | 3.27 | 3.27 |
| 326.40 | 2.49 | 2.49 |
| 298.35 | 1.71 | 1.71 |
| 304.35 | 3.18 | 3.18 |
| 254.29 | 2.05 | 2.05 |
| 410.56 | 4.83 | 4.83 |
| 284.32 | 1.67 | 1.67 |
| 340.43 | 2.88 | 2.88 |