Basic Information
ID: ALA4138641
Type: Binding
Description: Inhibition of PRMT1 (unknown origin) assessed as reduction in methyl transfer from [3H]-SAM to biotinylated histone H4 peptide H4-20-Biotin at 10 uM pre-incubated for 3 mins before [3H]-SAM addition and measured after 15 mins by scintillation proximity assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4138641
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 340.43 | 2.88 | 2.88 |
| 354.45 | 3.27 | 3.27 |
| 304.35 | 3.18 | 3.18 |
| 264.33 | 2.43 | 2.43 |
| 410.56 | 4.83 | 4.83 |