Basic Information
ID: ALA4138798
Type: Binding
Description: Inhibition of FAAH in rat brain microsomes assessed as reduction in enzyme-mediated 4-pyren-1-ylbutanoic acid release using N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide as substrate incubated fro 60 mins by reversed phase HPLC method
Format: BAO_0000251
Organism: Rattus norvegicus
Tissue: Brain
Subcellular Fraction: microsomes
Target: Anandamide amidohydrolase(ALA3229)
Document: ALA4138074
Inhibition of FAAH in rat brain microsomes assessed as reduction in enzyme-mediated 4-pyren-1-ylbutanoic acid release using N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide as substrate incubated fro 60 mins by reversed phase HPLC method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4138798
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 338.41 | 3.87 | 3.87 |
| 336.44 | 4.99 | 4.99 |
| 308.38 | 4.21 | 4.21 |
| 322.41 | 4.60 | 4.60 |
| 350.46 | 5.38 | 5.38 |
| 364.49 | 5.77 | 5.77 |
| 362.47 | 5.33 | 5.33 |
| 367.42 | 3.60 | 3.60 |
| 373.46 | 4.81 | 4.81 |
| 366.44 | 5.08 | 5.08 |
| 348.45 | 4.94 | 4.94 |
| 382.89 | 5.60 | 5.60 |
| 366.44 | 5.08 | 5.08 |
| 350.42 | 2.85 | 2.85 |
| 376.50 | 5.72 | 5.72 |
| 350.42 | 2.85 | 2.85 |
| 378.47 | 4.95 | 4.95 |
| 349.43 | 4.34 | 4.34 |
| 366.44 | 5.08 | 5.08 |
| 398.51 | 6.10 | 6.10 |
| 362.47 | 5.25 | 5.25 |
| 334.42 | 4.55 | 4.55 |
| 350.42 | 2.85 | 2.85 |
| 354.42 | 5.08 | 5.08 |
| 366.44 | 5.08 | 5.08 |