Basic Information
ID: ALA4139775
Type: Binding
Description: Inhibition of IL-15 (unknown origin)/IL-15Ralpha interaction in human PBMC cells assessed as reduction of TNF-alpha synthesis preincubated for 30 mins followed by IL-15 addition measured after 48 hrs by ELISA
Organism: Homo sapiens
Cell type: PBMC
Activity Charts
Bioactivity
Activity Types for Assay ALA4139775
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.52 | -0.64 | -0.64 |
| 226.24 | -1.13 | -1.13 |
| 182.23 | -0.58 | -0.58 |
| 318.40 | 3.17 | 3.17 |
| 251.24 | 0.87 | 0.87 |
| 303.31 | 1.92 | 1.92 |
| 374.38 | 1.34 | 1.34 |
| 330.34 | 2.79 | 2.79 |
| 398.42 | 3.37 | 3.37 |
| 352.30 | 0.99 | 0.99 |
| 279.29 | 1.04 | 1.04 |
| 182.17 | 1.19 | 1.19 |
| 215.22 | -3.82 | -3.82 |
| 305.33 | 1.89 | 1.89 |
| 303.31 | 1.67 | 1.67 |
| 317.34 | 1.75 | 1.75 |
| 212.26 | -1.32 | -1.32 |
| 351.34 | 1.89 | 1.89 |
| 320.26 | 0.97 | 0.97 |
| 232.28 | 0.15 | 0.15 |