Basic Information
ID: ALA4140811
Type: Functional
Description: In vivo inhibition of NMD in BALB/cA Jc1 nude mouse xenografted with human HCT116 cells assessed as upregulation of SC35 1.6 kb mRNA expression level in tumor at 100 mg/kg, po administered as single dose measured after 4 hrs by qPCR analysis relative to control
Organism: Mus musculus
Strain: BALB/cA Jc1
Activity Charts
Bioactivity
Activity Types for Assay ALA4140811
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 616.90 | 5.07 | 5.07 |
| 721.96 | 7.67 | 7.67 |