Assay Report Card

Basic Information

ID: ALA4140813

Type: Functional

Description: In vivo inhibition of NMD in BALB/cA Jc1 nude mouse xenografted with human HCT116 cells assessed as upregulation of SC35 1.6 kb mRNA expression level in tumor at 100 mg/kg, po administered as single dose measured after 24 hrs by qPCR analysis relative to control

Organism: Mus musculus

Strain: BALB/cA Jc1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
616.905.075.07
721.967.677.67