Basic Information
ID: ALA4141007
Type: Binding
Description: Inhibition of cathepsin D in human MDA-MB-231 cells using Mca-Gly-Lys-Pro-Ile-Leu-PhePhe-Arg-Leu-Lys-(Dnp)-D-Arg-NH2 as substrate pretreated for 4 hrs followed by compound washout and subsequent 10 mins trypsinization prior to substrate addition measured at 30 secs interval for 30 mins by fluorescence assay
Organism: Homo sapiens
Cell type: MDA-MB-231
Activity Charts
Bioactivity
Activity Types for Assay ALA4141007
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 685.90 | 1.47 | 1.47 |
| 1134.43 |