Assay Report Card

Basic Information

ID: ALA4141015

Type: Binding

Description: Inhibition of cathepsin D in human MDA-MB-231 cells assessed as reduction in cysteine cathepsin activity at 10 uM using Z-Phe-Arg-AMC as substrate pretreated for 3 days under pH 6.6 conditioned media followed by substrate addition measured at 5 mins interval for 2 hrs by ELISA relative to control

Organism: Homo sapiens

Cell type: MDA-MB-231

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1134.43