Assay Report Card

Basic Information

ID: ALA4141022

Type: Binding

Description: Inhibition of cathepsin D in human MDA-MB-231 cells assessed as reduction in tPA residual activity up to 10 uM incubated for 3 days under pH 6.6 conditioned media measured at 1 hr interval for 8 hrs by chromogenic method relative to control

Organism: Homo sapiens

Cell type: MDA-MB-231

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1134.43
959.200.540.54