Basic Information
ID: ALA4141645
Type: Binding
Description: Inhibition of MAO-A in rat liver mitochondria using p-tyramine as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins in presence of MAO-B inhibitor deprenyl by Amplex red dye-based fluorescence assay
Organism: Rattus norvegicus
Tissue: Liver
Subcellular Fraction: mitochondria
Activity Charts
Bioactivity
Activity Types for Assay ALA4141645
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 272.18 | 3.33 | 3.33 |
| 187.29 | 2.18 | 2.18 |
| 343.36 | 1.36 | 1.36 |
| 359.36 | 1.06 | 1.06 |
| 373.39 | 1.36 | 1.36 |
| 377.81 | 2.01 | 2.01 |
| 377.81 | 2.01 | 2.01 |
| 391.84 | 2.40 | 2.40 |
| 405.86 | 2.74 | 2.74 |
| 255.25 | -0.81 | -0.81 |
| 269.28 | -0.46 | -0.46 |
| 345.38 | 1.11 | 1.11 |
| 391.84 | 2.35 | 2.35 |
| 385.45 | 2.48 | 2.48 |
| 371.42 | 2.01 | 2.01 |
| 467.93 | 3.92 | 3.92 |
| 375.38 | 1.88 | 1.88 |
| 255.25 | 0.38 | 0.38 |
| 411.48 | 3.16 | 3.16 |
| 433.49 | 3.27 | 3.27 |
| 399.47 | 2.82 | 2.82 |
| 475.57 | 4.39 | 4.39 |
| 335.39 | 1.59 | 1.59 |
| 357.39 | 1.70 | 1.70 |
| 447.52 | 3.66 | 3.66 |
| 463.52 | 3.28 | 3.28 |
| 345.38 | 2.29 | 2.29 |
| 373.39 | 1.40 | 1.40 |
| 255.25 | 0.00 | 0.00 |
| 447.52 | 3.58 | 3.58 |
| 357.39 | 1.66 | 1.66 |
| 391.84 | 2.35 | 2.35 |
| 357.39 | 1.75 | 1.75 |
| 449.49 | 2.97 | 2.97 |
| 387.42 | 1.75 | 1.75 |
| 465.51 | 3.80 | 3.80 |
| 401.44 | 2.10 | 2.10 |
| 477.54 | 3.67 | 3.67 |
| 321.36 | 1.25 | 1.25 |
| 389.41 | 2.23 | 2.23 |
| 467.93 | 3.92 | 3.92 |
| 269.28 | 0.72 | 0.72 |
| 387.42 | 1.71 | 1.71 |
| 481.96 | 4.31 | 4.31 |
| 371.42 | 2.09 | 2.09 |