Basic Information
ID: ALA4142742
Type: Binding
Description: Positive allosteric modulation of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as acetyl choline-evoked currents at 10 uM at -80 mV holding potential prtreated for 2 mins followed by co-treatment with acetyl choline by electrophysiology method relative to acetyl choline
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4142742
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 258.27 | 2.62 | 2.62 |
| 553.45 | 2.65 | 2.65 |
| 537.45 | 2.94 | 2.94 |
| 274.27 | 2.32 | 2.32 |
| 634.57 | 2.93 | 2.93 |
| 551.43 | 2.73 | 2.73 |
| 650.57 | 2.64 | 2.64 |