Basic Information
ID: ALA4143309
Type: Binding
Description: Inhibition of recombinant Pseudomonas aeruginosa PAK His6-tagged ExoS ADPRT domain expressed in Escherichia coli using human GST-fused vH-Ras as substrate measured over 30 mins in presence of 14.3.3beta and epsilonNAD+ by fluorescence assay
Organism: Pseudomonas aeruginosa
Strain: PAK
Activity Charts
Bioactivity
Activity Types for Assay ALA4143309
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 206.27 | 1.86 | 1.86 |
| 266.26 | 2.29 | 2.29 |
| 232.24 | 1.33 | 1.33 |
| 300.35 | 1.26 | 1.26 |
| 262.26 | 1.34 | 1.34 |
| 276.32 | 1.66 | 1.66 |
| 286.33 | 2.21 | 2.21 |
| 280.30 | 0.46 | 0.46 |
| 216.20 | 1.02 | 1.02 |
| 277.35 | 1.87 | 1.87 |
| 291.38 | 1.54 | 1.54 |
| 276.32 | 1.66 | 1.66 |
| 304.37 | 2.44 | 2.44 |
| 246.27 | 1.72 | 1.72 |
| 299.30 | 1.32 | 1.32 |
| 258.28 | 1.43 | 1.43 |
| 272.30 | 1.82 | 1.82 |
| 300.34 | 2.67 | 2.67 |
| 292.36 | 2.27 | 2.27 |
| 250.23 | 1.47 | 1.47 |
| 278.33 | 1.58 | 1.58 |
| 280.30 | 0.46 | 0.46 |
| 278.33 | 1.81 | 1.81 |
| 355.44 | 0.87 | 0.87 |
| 292.36 | 2.27 | 2.27 |
| 277.24 | 1.24 | 1.24 |
| 272.30 | 1.82 | 1.82 |
| 292.36 | 2.29 | 2.29 |
| 312.35 | 2.84 | 2.84 |
| 262.29 | 1.57 | 1.57 |
| 263.32 | 1.78 | 1.78 |
| 297.33 | 2.13 | 2.13 |
| 272.30 | 1.82 | 1.82 |
| 258.28 | 1.43 | 1.43 |
| 256.22 | 1.88 | 1.88 |
| 234.25 | 1.35 | 1.35 |
| 268.22 | 1.61 | 1.61 |
| 263.32 | 0.89 | 0.89 |
| 280.30 | 1.07 | 1.07 |
| 278.33 | 1.44 | 1.44 |
| 326.38 | 2.76 | 2.76 |
| 280.30 | 1.07 | 1.07 |
| 272.30 | 1.82 | 1.82 |
| 252.66 | 1.59 | 1.59 |
| 286.33 | 2.21 | 2.21 |
| 276.32 | 1.66 | 1.66 |
| 264.31 | 1.49 | 1.49 |
| 262.29 | 1.57 | 1.57 |
| 250.32 | 1.40 | 1.40 |
| 278.33 | 1.88 | 1.88 |