Basic Information
ID: ALA4143485
Type: Binding
Description: Inhibition human recombinant GST-tagged Plk3 catalytic domain (58 to 340 residues) expressed in baculovirus expression system after 1 hr by FRET-based Z'-Lyte assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Serine/threonine-protein kinase PLK3(ALA4897)
Document: ALA4138231
Inhibition human recombinant GST-tagged Plk3 catalytic domain (58 to 340 residues) expressed in baculovirus expression system after 1 hr by FRET-based Z'-Lyte assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4143485
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 466.54 | 4.35 | 4.35 |
| 521.67 | 3.56 | 3.56 |
| 474.61 | 4.45 | 4.45 |
| 486.58 | 3.58 | 3.58 |
| 472.55 | 3.19 | 3.19 |
| 418.50 | 3.02 | 3.02 |
| 442.51 | 1.49 | 1.49 |
| 486.64 | 3.66 | 3.66 |
| 432.53 | 3.28 | 3.28 |
| 460.58 | 4.06 | 4.06 |
| 498.59 | 3.72 | 3.72 |
| 444.50 | 2.41 | 2.41 |
| 375.48 | 3.92 | 3.92 |
| 498.61 | 2.78 | 2.78 |
| 506.63 | 4.53 | 4.53 |
| 444.56 | 2.63 | 2.63 |
| 405.44 | 3.19 | 3.19 |
| 430.53 | 2.37 | 2.37 |
| 484.59 | 2.54 | 2.54 |
| 458.53 | 2.80 | 2.80 |
| 488.61 | 2.38 | 2.38 |
| 486.64 | 3.80 | 3.80 |
| 474.61 | 4.31 | 4.31 |
| 472.55 | 3.19 | 3.19 |
| 446.56 | 3.67 | 3.67 |
| 393.47 | 4.06 | 4.06 |
| 430.47 | 2.15 | 2.15 |
| 456.53 | 1.75 | 1.75 |
| 486.56 | 1.12 | 1.12 |
| 498.65 | 3.95 | 3.95 |
| 460.58 | 4.06 | 4.06 |
| 486.58 | 3.43 | 3.43 |
| 500.59 | 1.51 | 1.51 |
| 486.62 | 4.60 | 4.60 |
| 498.61 | 2.93 | 2.93 |
| 474.59 | 1.99 | 1.99 |
| 472.62 | 3.41 | 3.41 |