Basic Information
ID: ALA4143606
Type: Binding
Description: Inhibition of Norovirus 3CL protease using Edans-DFHLQ/GP-Dabcyl as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by FRET assay
Format: BAO_0000019
Organism: Norovirus
Target: Unchecked(ALA612545)
Document: ALA4138240
Inhibition of Norovirus 3CL protease using Edans-DFHLQ/GP-Dabcyl as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4143606
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 584.02 | 1.17 | 1.17 |
| 608.09 | 2.26 | 2.26 |
| 568.02 | 1.34 | 1.34 |
| 504.03 | 3.25 | 3.25 |
| 493.99 | 2.30 | 2.30 |
| 479.96 | 2.16 | 2.16 |
| 463.96 | 2.33 | 2.33 |
| 598.05 | 1.31 | 1.31 |