Basic Information
ID: ALA4143723
Type: Binding
Description: Competitive inhibition of NAE (unknown origin) assessed as decrease in NAE-mediated Ubc12-NEDD8 conjugation levels at 10 uM preincubated for 10 mins followed by Mg2+ and various concentrations of ATP addition measured after 60 mins by Lineweaver-Burk plot analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4143723
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 444.49 | -0.14 | -0.14 |
| 443.53 | 2.06 | 2.06 |