Basic Information
ID: ALA4143724
Type: Binding
Description: Inhibition of NAE (unknown origin) assessed as decrease in NAE-mediated Ubc12-NEDD8 conjugation levels at 10 uM treated for 10 mins post ATP and Mg2+ addition measured after 60 mins by Western blot analysis
Format: BAO_0000223
Organism: Homo sapiens
Target: NEDD8 activating enzyme(ALA3831283)
Document: ALA4138244
Inhibition of NAE (unknown origin) assessed as decrease in NAE-mediated Ubc12-NEDD8 conjugation levels at 10 uM treated for 10 mins post ATP and Mg2+ addition measured after 60 mins by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4143724
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 444.49 | -0.14 | -0.14 |