Assay Report Card

Basic Information

ID: ALA4143728

Type: Binding

Description: Inhibition of NAE in human Caco2 cells assessed as increase in p53 protein levels by measuring p53 degradation at 10 uM preincubated for 16 hrs followed by cycloheximide addition measured up to 60 mins by Western blot analysis relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
444.49-0.14-0.14