Basic Information
ID: ALA4144007
Type: Functional
Description: Antagonist activity at recombinant human LPA1 expressed in CHO cells assessed as reduction in LPA-induced intracellular calcium level pretreated followed by LPA addition by Fura-2-AM dye based fluorescence assay
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA4144007
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 461.56 | 4.91 | 4.91 |
| 459.54 | 5.00 | 5.00 |
| 462.59 | 5.55 | 5.55 |
| 480.61 | 4.83 | 4.83 |
| 466.58 | 4.60 | 4.60 |
| 465.59 | 5.20 | 5.20 |
| 457.59 | 4.88 | 4.88 |
| 477.60 | 4.99 | 4.99 |
| 452.55 | 4.21 | 4.21 |
| 460.57 | 5.70 | 5.70 |
| 463.57 | 4.60 | 4.60 |
| 452.55 | 4.21 | 4.21 |
| 451.56 | 4.81 | 4.81 |
| 457.59 | 4.88 | 4.88 |
| 471.62 | 5.27 | 5.27 |
| 466.58 | 4.60 | 4.60 |
| 471.62 | 5.27 | 5.27 |
| 452.55 | 4.21 | 4.21 |
| 437.54 | 4.88 | 4.88 |