Basic Information
ID: ALA4144310
Type: Functional
Description: Antagonist activity at CXCR4 in human CCRF-CEM cells assessed as inhibition of SDF1alpha-induced calcium flux pretreated for 25 mins followed by SDF1alpha addition measured for 90 secs by calcium dye-based fluorescence assay
Organism: Homo sapiens
Cell type: CCRF-CEM
Activity Charts
Bioactivity
Activity Types for Assay ALA4144310
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 364.54 | 3.21 | 3.21 |
| 352.53 | 3.21 | 3.21 |
| 354.50 | 2.35 | 2.35 |
| 342.46 | 2.48 | 2.48 |
| 374.53 | 3.49 | 3.49 |
| 356.49 | 2.78 | 2.78 |
| 358.92 | 2.99 | 2.99 |
| 392.47 | 3.36 | 3.36 |
| 378.56 | 3.52 | 3.52 |
| 358.92 | 2.99 | 2.99 |
| 352.53 | 3.21 | 3.21 |
| 338.50 | 2.65 | 2.65 |
| 330.50 | 2.40 | 2.40 |
| 364.54 | 3.21 | 3.21 |
| 338.50 | 2.90 | 2.90 |
| 338.50 | 2.65 | 2.65 |
| 342.46 | 2.48 | 2.48 |
| 344.53 | 2.71 | 2.71 |
| 352.53 | 2.95 | 2.95 |
| 354.50 | 2.35 | 2.35 |
| 366.51 | 2.66 | 2.66 |
| 374.53 | 3.49 | 3.49 |
| 358.92 | 2.99 | 2.99 |
| 356.49 | 2.78 | 2.78 |
| 338.50 | 2.65 | 2.65 |
| 392.47 | 3.36 | 3.36 |
| 324.47 | 2.34 | 2.34 |
| 338.50 | 2.65 | 2.65 |
| 374.53 | 3.49 | 3.49 |
| 350.51 | 2.98 | 2.98 |
| 330.50 | 2.40 | 2.40 |