Basic Information
ID: ALA4144370
Type: Binding
Description: Activation of CaMKK2-phosphorylated AMPK10 alpha2/beta2/gamma1 (unknown origin) assessed as ratio of 5-(6-chloro-5-(1-methyl-1H-indol-5-yl)-1H-benzo[d]imidazol-2-yloxy)-2-methylbenzoic acid EC50 to test compound EC50 using fluorescein-labeled SAMS peptide as substrate pretreated for 30 mins in presence of AMP followed by substrate addition measured after 60 mins by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4144370
Ratio EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.91 | 7.35 | 7.35 |
| 448.47 | 6.20 | 6.20 |
| 449.89 | 3.85 | 3.85 |
| 450.44 | 5.19 | 5.19 |
| 441.48 | 5.13 | 5.13 |
| 440.93 | 4.90 | 4.90 |