Basic Information
ID: ALA4144642
Type: Binding
Description: Agonist activity at PPARgamma in LPS-stimulated mouse RAW264.7 cells assessed as inhibition of NF-kappaB signaling by measuring reduction in IL-6 mRNA level at 50 uM pretreated with compound for 1 hr followed by LPS stimulation for 6 hrs by RT-PCR analysis relative to control
Format: BAO_0000219
Organism: Mus musculus
Cell type: RAW264.7
Target: Peroxisome proliferator-activated receptor gamma(ALA2459)
Document: ALA4138282
Agonist activity at PPARgamma in LPS-stimulated mouse RAW264.7 cells assessed as inhibition of NF-kappaB signaling by measuring reduction in IL-6 mRNA level at 50 uM pretreated with compound for 1 hr followed by LPS stimulation for 6 hrs by RT-PCR analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4144642
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 332.44 | 4.57 | 4.57 |