Assay Report Card

Basic Information

ID: ALA4144875

Type: Functional

Description: Antiviral activity against human respiratory syncytial virus A2 infected in Balb/c mouse assessed as reduction in lung viral load at 50 mg/kg, po administered once daily pretreated for 1 hr on day 0 followed by viral infection and subsequent compound dosing for 3 days measured after 1 day post last dose by plaque assay

Organism: Human respiratory syncytial virus

Strain: A2

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
377.452.702.70
541.454.224.22