Basic Information
ID: ALA4144878
Type: Binding
Description: Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected Sf9 insect cells using histone H3 (1 to 50 residues)-GGK as substrate after 2 hrs in presence of SAM by fluorescence assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4144878
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 572.75 | 4.73 | 4.73 |
| 476.42 | 4.00 | 4.00 |
| 579.74 | 3.68 | 3.68 |
| 451.57 | 4.24 | 4.24 |
| 487.98 | 4.34 | 4.34 |
| 564.73 | 4.92 | 4.92 |
| 467.57 | 3.94 | 3.94 |
| 491.51 | 4.69 | 4.69 |
| 576.78 | 5.82 | 5.82 |
| 521.54 | 4.70 | 4.70 |
| 507.51 | 4.39 | 4.39 |
| 493.60 | 4.56 | 4.56 |
| 453.61 | 4.45 | 4.45 |
| 471.53 | 3.82 | 3.82 |
| 550.70 | 4.07 | 4.07 |
| 467.57 | 3.99 | 3.99 |
| 548.73 | 5.04 | 5.04 |
| 467.57 | 3.99 | 3.99 |
| 453.54 | 3.68 | 3.68 |
| 478.55 | 3.55 | 3.55 |
| 439.51 | 3.37 | 3.37 |
| 437.54 | 3.98 | 3.98 |
| 443.93 | 4.02 | 4.02 |
| 566.70 | 3.77 | 3.77 |
| 451.57 | 4.29 | 4.29 |