Basic Information
ID: ALA4144917
Type: Binding
Description: Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and C10-CoA as substrate pretreated for 15 mins followed by substrate addition measured after 60 mins by CPM dye based fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4144917
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 462.93 | 6.26 | 6.26 |
| 414.46 | 5.22 | 5.22 |
| 510.51 | 7.02 | 7.02 |
| 456.54 | 6.31 | 6.31 |
| 442.52 | 6.00 | 6.00 |
| 476.96 | 6.65 | 6.65 |
| 472.54 | 6.01 | 6.01 |
| 510.51 | 7.02 | 7.02 |
| 458.51 | 5.62 | 5.62 |
| 476.96 | 6.65 | 6.65 |
| 496.49 | 6.63 | 6.63 |
| 510.51 | 7.02 | 7.02 |
| 510.51 | 7.02 | 7.02 |
| 442.52 | 5.92 | 5.92 |
| 428.49 | 5.61 | 5.61 |
| 456.54 | 6.31 | 6.31 |
| 476.96 | 6.65 | 6.65 |
| 456.54 | 6.39 | 6.39 |
| 446.48 | 5.75 | 5.75 |
| 476.96 | 6.65 | 6.65 |
| 460.51 | 6.14 | 6.14 |
| 496.49 | 6.54 | 6.54 |
| 510.51 | 7.02 | 7.02 |