Basic Information
ID: ALA4144984
Type: Binding
Description: Inverse agonist activity at APC-labeled RORgammat LBD (unknown origin) assessed as inhibition of N-(2-chloro-6-fluorobenzyl)-N-((2'-methoxy-[1,1'-biphenyl]-4-yl)methyl)benzenesulfonamide-induced co-activator SRC1 peptide recruitment after 1 hr by FRET based LANCE assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4144984
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 490.61 | 5.02 | 5.02 |
| 481.92 | 6.00 | 6.00 |
| 611.69 | 6.02 | 6.02 |
| 532.69 | 6.14 | 6.14 |
| 546.71 | 6.21 | 6.21 |
| 472.49 | 5.22 | 5.22 |
| 653.77 | 7.05 | 7.05 |
| 413.46 | 4.80 | 4.80 |
| 568.66 | 7.34 | 7.34 |
| 558.73 | 6.67 | 6.67 |
| 528.60 | 6.42 | 6.42 |
| 504.63 | 5.32 | 5.32 |
| 447.48 | 5.35 | 5.35 |
| 663.20 | 7.83 | 7.83 |