Inhibition of recombinant HIV1 protease at 1 nM using H-Lys-Ala-Arg-Val-Tyr-Phe(p-NO2)-Glu-Ala-Nle-NH2 as substrate preincubated for 5 mins followed b...

Basic Information

ID: ALA4145128

Type: Binding

Description: Inhibition of recombinant HIV1 protease at 1 nM using H-Lys-Ala-Arg-Val-Tyr-Phe(p-NO2)-Glu-Ala-Nle-NH2 as substrate preincubated for 5 mins followed by substrate addition measured after 3 hrs by fluorescence-based assay

Format: BAO_0000357

Organism: Human immunodeficiency virus 1

Target: Protease(ALA2366517)

Document: ALA4138310

Inhibition of recombinant HIV1 protease at 1 nM using H-Lys-Ala-Arg-Val-Tyr-Phe(p-NO2)-Glu-Ala-Nle-NH2 as substrate preincubated for 5 mins followed by substrate addition measured after 3 hrs by fluorescence-based assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4145128

Inhibition

Total(23)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
575.73	3.71	3.71
667.85	2.37	2.37
726.90	4.27	4.27
767.95	3.84	3.84
808.01	5.03	5.03
743.88	3.12	3.12
698.89	4.89	4.89
757.95	3.22	3.22
773.95	2.20	2.20
724.88	3.16	3.16
713.86	3.11	3.11
728.91	4.90	4.90
681.86	1.72	1.72
724.88	3.16	3.16
759.97	3.35	3.35
754.91	3.63	3.63
753.92	3.53	3.53
709.91	2.48	2.48
756.92	4.28	4.28
723.90	3.76	3.76
695.88	2.11	2.11
711.88	1.09	1.09
723.90	3.76	3.76