Basic Information
ID: ALA4145211
Type: Binding
Description: Binding affinity to PARP1 in human OVCAR8 cells assessed as reduction in [125I]-KX1 binding by gamma counting analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4145211
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 434.47 | 2.35 | 2.35 |
| 395.43 | 2.90 | 2.90 |
| 506.58 | 4.13 | 4.13 |
| 378.41 | 1.84 | 1.84 |
| 406.46 | 2.62 | 2.62 |
| 377.42 | 3.28 | 3.28 |
| 488.56 | 3.52 | 3.52 |
| 474.54 | 3.13 | 3.13 |
| 377.42 | 3.42 | 3.42 |
| 391.45 | 3.67 | 3.67 |
| 434.52 | 3.26 | 3.26 |
| 405.47 | 4.06 | 4.06 |
| 474.54 | 3.13 | 3.13 |
| 378.41 | 1.70 | 1.70 |
| 392.43 | 2.09 | 2.09 |
| 433.53 | 4.84 | 4.84 |
| 406.46 | 2.48 | 2.48 |
| 419.50 | 4.45 | 4.45 |
| 506.58 | 4.27 | 4.27 |
| 379.39 | 2.13 | 2.13 |
| 405.47 | 4.06 | 4.06 |
| 478.52 | 3.49 | 3.49 |
| 420.49 | 2.87 | 2.87 |
| 492.55 | 3.74 | 3.74 |
| 446.48 | 2.49 | 2.49 |
| 406.46 | 2.48 | 2.48 |
| 446.48 | 2.35 | 2.35 |
| 502.59 | 3.91 | 3.91 |
| 460.51 | 2.74 | 2.74 |
| 506.58 | 4.13 | 4.13 |
| 520.61 | 4.52 | 4.52 |
| 405.47 | 4.20 | 4.20 |
| 478.52 | 3.35 | 3.35 |
| 474.54 | 3.27 | 3.27 |
| 534.63 | 4.91 | 4.91 |