Induction of DNA double strand breaks in human OVCAR8 cells assessed as increase in gamma-H2AX expression at 10 uM after 24 hrs by DAPI-based fluoresc...

Basic Information

ID: ALA4145214

Type: ADME

Description: Induction of DNA double strand breaks in human OVCAR8 cells assessed as increase in gamma-H2AX expression at 10 uM after 24 hrs by DAPI-based fluorescence microscopy

Format: BAO_0000219

Organism: Homo sapiens

Cell type: OVCAR-8

Target: OVCAR-8(ALA612555)

Document: ALA4138313

Induction of DNA double strand breaks in human OVCAR8 cells assessed as increase in gamma-H2AX expression at 10 uM after 24 hrs by DAPI-based fluorescence microscopy: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4145214

Activity

Total(1)

Parent Molecular Weight	ALogP	Polar Surface Area
446.48	2.35	2.35

Parent Molecular Weight

ALogP

Polar Surface Area

446.48

2.35

Induction of DNA double strand breaks in human OVCAR8 cells assessed as increase in gamma-H2AX expression at 10 uM after 24 hrs by DAPI-based fluoresc...

Basic Information

Activity Charts

Compound Summary