Basic Information
ID: ALA4145315
Type: Functional
Description: Antagonist activity at human MOR expressed in CHO cell membranes mixed with human DOR expressed in CHO cell membranes assessed as inhibition of CYM51010-induced [35S]-GTPgammaS binding preincubated for 5 mins followed by CYM51010 and [35S]-GTPgammaS addition measured after 80 mins
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Opioid receptors; mu & delta(ALA2095149)
Document: ALA4138315
Antagonist activity at human MOR expressed in CHO cell membranes mixed with human DOR expressed in CHO cell membranes assessed as inhibition of CYM51010-induced [35S]-GTPgammaS binding preincubated for 5 mins followed by CYM51010 and [35S]-GTPgammaS addition measured after 80 mins: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4145315
IC50L
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1385.63 |