Basic Information
ID: ALA4145318
Type: Functional
Description: Antagonist activity at human mu-delta opioid receptor heterodimer expressed in CHO cell membranes assessed as inhibition of CYM51010-induced [35S]-GTPgammaS binding at high site fraction preincubated for 5 mins followed by CYM51010 and [35S]-GTPgammaS addition measured after 80 mins relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Opioid receptors; mu & delta(ALA2095149)
Document: ALA4138315
Antagonist activity at human mu-delta opioid receptor heterodimer expressed in CHO cell membranes assessed as inhibition of CYM51010-induced [35S]-GTPgammaS binding at high site fraction preincubated for 5 mins followed by CYM51010 and [35S]-GTPgammaS addition measured after 80 mins relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4145318
Imax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1385.63 | ||
| 1683.97 | ||
| 1244.42 | ||
| 340.38 | 1.30 | 1.30 |
| 1343.55 | ||
| 1484.76 | ||
| 610.71 | -0.07 | -0.07 |
| 1286.50 |