Basic Information
ID: ALA4145322
Type: Functional
Description: Antagonist activity at human mu-delta opioid receptor heterodimer expressed in CHO cell membranes assessed as inhibition of DAMGO-induced [35S]-GTPgammaS binding preincubated for 5 mins followed by DAMGO and [35S]-GTPgammaS addition measured after 80 mins
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Opioid receptors; mu & delta(ALA2095149)
Document: ALA4138315
Antagonist activity at human mu-delta opioid receptor heterodimer expressed in CHO cell membranes assessed as inhibition of DAMGO-induced [35S]-GTPgammaS binding preincubated for 5 mins followed by DAMGO and [35S]-GTPgammaS addition measured after 80 mins: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4145322
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 621.74 | 2.35 | 2.35 |
| 1385.63 | ||
| 340.38 | 1.30 | 1.30 |