Assay Report Card

Basic Information

ID: ALA4145401

Type: Functional

Description: Antitumor activity against ABCB1 overexpressing human SW620/AD300 cells xenografted in BALB/c nude mouse assessed as reduction in tumor volume at 20 mg/kg/day, po cotreated with 5 mg/kg, ip paclitaxel measured after 21 days

Organism: Homo sapiens

Cell type: SW620/AD300

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
606.065.275.27