Basic Information
ID: ALA4146152
Type: Binding
Description: Inhibition of Mycobacterium tuberculosis H37Rv DHFR expressed in Escherichia coli BL21(DE3) assessed as reduction in consumption of NADPH using DHF as substrate preincubated for 1 min followed by DHF addition and measured for 2 mins by spectrophotometric method
Organism: Mycobacterium tuberculosis H37Rv
Activity Charts
Bioactivity
Activity Types for Assay ALA4146152
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 482.50 | 0.45 | 0.45 |
| 510.56 | 1.23 | 1.23 |