Basic Information
ID: ALA4146167
Type: Binding
Description: Inhibition of recombinant human DHFR assessed as reduction in consumption of NADPH using DHF as substrate measured every 30 secs over 6 mins by spectrophotometric method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4146167
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.45 | 0.27 | 0.27 |
| 509.06 | 3.60 | 3.60 |
| 607.12 | 3.93 | 3.93 |
| 529.05 | 2.74 | 2.74 |
| 593.09 | 3.54 | 3.54 |